Title : Increased iNOS activity is essential for hepatic epithelial tight junction dysfunction in endotoxemic mice.

Pub. Date : 2004 Jan

PMID : 12946943






1 Functional Relationships(s)
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1 Pharmacological inhibition of iNOS activity using l-N6-(1-iminoethyl)lysine (5 mg/kg) or genetic ablation of iNOS ameliorated LPS-induced changes in hepatobiliary barrier function, and these strategies partially preserved TJ protein expression and localization. N(6)-(1-iminoethyl)lysine nitric oxide synthase 2, inducible Mus musculus