Title : CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes.

Pub. Date : 2003 Sep 15

PMID : 12919724






1 Functional Relationships(s)
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1 These results show that acute/subacute benzene and acute toluene treatments induce CYP2E1 expression probably through a similar mechanism which might be different from that of pyridine or acetone, in that the former increase mRNA levels, both in liver and in peripheral lymphocytes, whereas the latter stabilized the apo-protein. Toluene cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus