Pub. Date : 2003 Aug
PMID : 12897087
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Up-regulation of organic anion transporter 1 protein is induced by chronic furosemide or hydrochlorothiazide infusion in rat kidney. | Hydrochlorothiazide | solute carrier family 22 member 6 | Rattus norvegicus |
| 2 | OAT1 protein abundance in cortical homogenates was also increased by hydrochlorothiazide infusion (181 +/- 25 vs 100 +/- 7%, P < 0.01), whereas Na-K-ATPase alpha1 subunit protein abundance was not affected (105 +/- 4 vs 100 +/- 4%, P = 0.34). | Hydrochlorothiazide | solute carrier family 22 member 6 | Rattus norvegicus |
| 3 | CONCLUSION: Chronic furosemide or hydrochlorothiazide infusion caused increases in OAT1 protein abundance in rat kidney. | Hydrochlorothiazide | solute carrier family 22 member 6 | Rattus norvegicus |