Title : Up-regulation of organic anion transporter 1 protein is induced by chronic furosemide or hydrochlorothiazide infusion in rat kidney.

Pub. Date : 2003 Aug

PMID : 12897087






3 Functional Relationships(s)
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Protein Name
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1 Up-regulation of organic anion transporter 1 protein is induced by chronic furosemide or hydrochlorothiazide infusion in rat kidney. Hydrochlorothiazide solute carrier family 22 member 6 Rattus norvegicus
2 OAT1 protein abundance in cortical homogenates was also increased by hydrochlorothiazide infusion (181 +/- 25 vs 100 +/- 7%, P < 0.01), whereas Na-K-ATPase alpha1 subunit protein abundance was not affected (105 +/- 4 vs 100 +/- 4%, P = 0.34). Hydrochlorothiazide solute carrier family 22 member 6 Rattus norvegicus
3 CONCLUSION: Chronic furosemide or hydrochlorothiazide infusion caused increases in OAT1 protein abundance in rat kidney. Hydrochlorothiazide solute carrier family 22 member 6 Rattus norvegicus