Title : Oxidative stimuli affect polyglutamine aggregation and cell death in human mutant ataxin-1-expressing cells.

Pub. Date : 2003 Sep 4

PMID : 12893416






1 Functional Relationships(s)
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1 Treatment of cells with buthionine sulfoximine, hydrogen peroxide or t-butylhydroperoxide increased the formation of mutant ataxin-1 aggregates, but treatment with the anti-oxidant, N-acetylcysteine (NAC), decreased aggregate formation. tert-Butylhydroperoxide ataxin 1 Homo sapiens