Title : Cross-linking of actin filaments by myosin II is a major contributor to cortical integrity and cell motility in restrictive environments.

Pub. Date : 2003 Sep 15

PMID : 12890752






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cells lacking myosin II heavy chain (mhcA-) are unable to migrate under agarose overlays of greater than 0.5%, and even at this concentration they move only a short distance from the trough. Sepharose myosin heavy chain 14 Homo sapiens
2 Consistent with a role for myosin II in general cortical stability, GFP-myosin dynamically localizes to the lateral and posterior cortex of cells moving under agarose. Sepharose myosin heavy chain 14 Homo sapiens