Title : Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase.

Pub. Date : 2003 Sep 26

PMID : 12871934






1 Functional Relationships(s)
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1 Here we show that LRP1 is differentially glycosylated in a tissue-specific manner and that carbohydrate addition reduces proteolytic cleavage of the extracellular domain and, concomitantly, ICD release. Carbohydrates LDL receptor related protein 1 Homo sapiens