Title : Prevalence of necrosis in C2-ceramide-induced cytotoxicity in NB16 neuroblastoma cells.

Pub. Date : 2003 Aug

PMID : 12869656






1 Functional Relationships(s)
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1 Both C2-ceramide and TNFalpha + CHX increased caspase 8- and 3-like activities in cytosolic extracts; however, treatment of cells with the broad-spectrum caspase inhibitor N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone protected NB16 cells from TNFalpha + CHX-induced cell death but did not prevent C2-ceramide cytotoxicity. Caspase Inhibitor VI caspase 8 Homo sapiens