Title : The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation.

Pub. Date : 2003 Oct

PMID : 12869591






5 Functional Relationships(s)
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Protein Name
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1 The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation. Cisplatin heat shock protein 90 alpha family class A member 1 Homo sapiens
2 Cisplatin may also disrupt the function of some proteins, including heat shock protein 90 (Hsp90). Cisplatin heat shock protein 90 alpha family class A member 1 Homo sapiens
3 Cisplatin may also disrupt the function of some proteins, including heat shock protein 90 (Hsp90). Cisplatin heat shock protein 90 alpha family class A member 1 Homo sapiens
4 Immunoprecipitation revealed that cisplatin disrupts binding of GR to Hsp90. Cisplatin heat shock protein 90 alpha family class A member 1 Homo sapiens
5 Moreover, cisplatin-treated Hsp90 was unable to associate with untreated ligand binding domain of GR. Cisplatin heat shock protein 90 alpha family class A member 1 Homo sapiens