Pub. Date : 2003 Oct 3
PMID : 12855709
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Natriuretic peptide binding to type I receptors (NPRA and NPRB) activates their intrinsic guanylyl cyclase activity, resulting in a rapid increase in cytosolic cGMP that subsequently activates PKG. | Cyclic GMP | natriuretic peptide receptor 1 | Homo sapiens |
| 2 | As such, the NPRA-PKG association may represent a novel mechanism for compartmentation of cGMP-mediated signaling and regulation of receptor sensitivity. | Cyclic GMP | natriuretic peptide receptor 1 | Homo sapiens |