Pub. Date : 2003 Jul
PMID : 12855625
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The purpose of this study was to evaluate the bioavailability and efficacy of a novel antisense phosphorodiamidate morpholino oligomer directed against c-myc, AVI-4126, in PC-3 androgen-independent human prostate cancer xenograft murine model and its safety in a Phase I human clinical study. | phosphorodiamidate morpholino | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | CONCLUSIONS: The present study demonstrates that inhibition of c-Myc expression by antisense phosphorodiamidate morpholino oligomer is a promising new and safe therapeutic strategy for prostate cancer. | phosphorodiamidate morpholino | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |