Title : [Modulation of 3,4-diaminopyridine-evoked norepinephrine release from rat hippocampal slices by activation of alpha 2-adrenoceptor].

Pub. Date : 1992 Nov

PMID : 1284575






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Clonidine and yohimbine inhibited and enhanced the 3,4-DAP-evoked [3H]NE release in a concentration-dependent manner both in the presence and absence of extracellular Ca2+. Clonidine death-associated protein Rattus norvegicus
2 In the presence of extracellular Ca2+ the clonidine effect was not altered by addition of omega-conotoxin GVIA 0.1 mumol.L-1 or by removal of extracellular Ca2+, suggesting that the Ca2+ entry was not involved in the modulatory mechanisms of DAP-evoked [3H]NE release by activation of alpha 2-receptor. Clonidine death-associated protein Rattus norvegicus