Pub. Date : 2003 Jul
PMID : 12843192
6 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | PD98059 (1 micro M) inhibited IGF-I-induced MAPK activity by 94%. | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | insulin like growth factor 1 | Homo sapiens | ||
| 2 | In the presence of 1 micro M PD98059, IGF-I-induced stimulation of progesterone production was inhibited by 96% (P < 0.001). | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | insulin like growth factor 1 | Homo sapiens | ||
| 3 | The inhibitory effect of IGF-I on IGFBP-1 production was reduced in the presence of 1 micro M PD98059 by 45% at 5 ng/ml IGF-I and was completely abolished in the presence of 1 micro M PD98059 at concentrations of IGF-I ranging from 0.5-2.5 ng/ml (P < 0.001). | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | insulin like growth factor 1 | Homo sapiens | ||
| 4 | The inhibitory effect of IGF-I on IGFBP-1 production was reduced in the presence of 1 micro M PD98059 by 45% at 5 ng/ml IGF-I and was completely abolished in the presence of 1 micro M PD98059 at concentrations of IGF-I ranging from 0.5-2.5 ng/ml (P < 0.001). | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | insulin like growth factor 1 | Homo sapiens | ||
| 5 | The inhibitory effect of IGF-I on IGFBP-1 production was reduced in the presence of 1 micro M PD98059 by 45% at 5 ng/ml IGF-I and was completely abolished in the presence of 1 micro M PD98059 at concentrations of IGF-I ranging from 0.5-2.5 ng/ml (P < 0.001). | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | insulin like growth factor 1 | Homo sapiens | ||
| 6 | The inhibitory effect of IGF-I on IGFBP-1 production was reduced in the presence of 1 micro M PD98059 by 45% at 5 ng/ml IGF-I and was completely abolished in the presence of 1 micro M PD98059 at concentrations of IGF-I ranging from 0.5-2.5 ng/ml (P < 0.001). | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | insulin like growth factor 1 | Homo sapiens | ||