Title : Differential effect of IL-18 on endothelial cell apoptosis mediated by TNF-alpha and Fas (CD95).

Pub. Date : 2003 Jun 7

PMID : 12842762






1 Functional Relationships(s)
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1 Partial blocking of LEC apoptosis induced by IL-18 and TNF was observed when the cells were pretreated with the broad-spectrum inhibitor of caspases z-VAD-fmk, suggesting involvement of the caspase pathway in apoptosis induced by these cytokines in these cells. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone tumor necrosis factor Homo sapiens