Title : Is timing everything? Therapeutic potential of modulators of cardiac Na(+) transporters.

Pub. Date : 2003 Jul

PMID : 12831348






1 Functional Relationships(s)
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1 As the benefits of NHE1 inhibitors (e.g., amiloride, cariporide) in models of myocardial infarction are usually much greater when used as pretreatment, rather than during or after ischaemia, it is probably not surprising that clinical trials with cariporide in ischaemia have shown little shortterm benefit. Amiloride solute carrier family 9 member A1 Homo sapiens