Title : Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1.

Pub. Date : 2003 Jun

PMID : 12820976






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Remarkably, SMUG1 also excises the oxidation-damage product 5-hydroxymethyluracil (HmU), but like UNG is inactive against thymine (5-methyluracil), a chemical substructure of HmU. 5-hydroxymethyluracil single-strand-selective monofunctional uracil-DNA glycosylase 1 Homo sapiens
2 Remarkably, SMUG1 also excises the oxidation-damage product 5-hydroxymethyluracil (HmU), but like UNG is inactive against thymine (5-methyluracil), a chemical substructure of HmU. 5-hydroxymethyluracil single-strand-selective monofunctional uracil-DNA glycosylase 1 Homo sapiens
3 Remarkably, SMUG1 also excises the oxidation-damage product 5-hydroxymethyluracil (HmU), but like UNG is inactive against thymine (5-methyluracil), a chemical substructure of HmU. 5-hydroxymethyluracil single-strand-selective monofunctional uracil-DNA glycosylase 1 Homo sapiens