Title : cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension.

Pub. Date : 2003 Sep 12

PMID : 12819211






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Analogs modified in the 2"-position of the ribose induced stronger Epac1 activation than cAMP but were only partial agonists for cAPK. Ribose Rap guanine nucleotide exchange factor 3 Rattus norvegicus