Title : Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization.

Pub. Date : 2003 Sep 5

PMID : 12815037






1 Functional Relationships(s)
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1 The agonist-induced increase in KOR-P labeling was dose-dependent, blocked by co-treatment with the kappa antagonist norbinaltorphimine, and prevented by co-expression of the dominant negative form of the G-protein receptor kinase, GRK2(K220R). norbinaltorphimine opioid receptor kappa 1 Homo sapiens