Pub. Date : 2003 Jun
PMID : 12800232
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present study was to investigate the cell killing action of TRAIL on colon cancer cell line SW480, its synergistic effect with doxorubicin, and the possible mechanisms. | Doxorubicin | TNF superfamily member 10 | Homo sapiens |
| 2 | (3) TRAIL could synergize with doxorubicin to kill SW480 cells effectively, which was represented by the boosted killing effect of doxorubicin on theses cells. | Doxorubicin | TNF superfamily member 10 | Homo sapiens |
| 3 | (3) TRAIL could synergize with doxorubicin to kill SW480 cells effectively, which was represented by the boosted killing effect of doxorubicin on theses cells. | Doxorubicin | TNF superfamily member 10 | Homo sapiens |
| 4 | IC(50) of doxorubicin against SW480 cells sharply reduced when it was combined with TRAIL. | Doxorubicin | TNF superfamily member 10 | Homo sapiens |
| 5 | CONCLUSION: SW480 cells are not sensitive to TRAIL, but TRAIL can synergize with lower concentration of doxorubicin to induce apoptosis effectively. | Doxorubicin | TNF superfamily member 10 | Homo sapiens |