Title : LacSwitch II regulation of connexin43 cDNA expression enables gap-junction single-channel analysis.

Pub. Date : 2003 May

PMID : 12765030






2 Functional Relationships(s)
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Protein Name
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1 To regulate the expression of connexins in cells, plasmids encoding a transactivator and/or a lac-operon IPTG response-dependent Cx43 target gene were transfected into communication-deficient N2a neuroblastoma cells. Isopropyl Thiogalactoside gap junction protein, alpha 3 Mus musculus
2 Chronic induction at specific doses of IPTG produced constant, controlled levels of Cx43 expression, which were reflected by predictable junctional coupling levels. Isopropyl Thiogalactoside gap junction protein, alpha 3 Mus musculus