Pub. Date : 2003 May
PMID : 12753742
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here we show that upon TNFalpha binding, TNFR1 translocates to cholesterol- and sphingolipid-enriched membrane microdomains, termed lipid rafts, where it associates with the Ser/Thr kinase RIP and the adaptor proteins TRADD and TRAF2, forming a signaling complex. | Sphingolipids | tumor necrosis factor | Homo sapiens |