Pub. Date : 2003 Jul 25
PMID : 12748191
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Saccharomyces cerevisiae PIP2 mediating oleic acid induction and peroxisome proliferation is regulated by Adr1p and Pip2p-Oaf1p. | Oleic Acid | oleate-activated transcription factor PIP2 | Saccharomyces cerevisiae S288C |
| 2 | Immunoprecipitation showed that, in adr1delta mutant cells grown on oleic acid, Pip2p was less abundant compared with the corresponding wild-type. | Oleic Acid | oleate-activated transcription factor PIP2 | Saccharomyces cerevisiae S288C |
| 3 | Transcription of the oleic acid-inducible genes SPS19 and CTA1, which rely on both Pip2p-Oaf1p and Adr1p for their regulation, was reduced in adr1delta mutant cells. | Oleic Acid | oleate-activated transcription factor PIP2 | Saccharomyces cerevisiae S288C |
| 4 | However, by ectopically restoring levels of Pip2p in adr1delta cells grown on oleic acid medium, transcription of both genes increased 2-fold compared with the control. | Oleic Acid | oleate-activated transcription factor PIP2 | Saccharomyces cerevisiae S288C |