Title : Attenuation of cerebral vasospasm in rabbits using clonidine hydrochloride, a central adrenergic agonist.

Pub. Date : 2003 Apr 30

PMID : 12742193






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1 The results of this study demonstrated that the central alpha(2)-blocker clonidine hydrochloride effectively prevents vasospasm, and diminishes the concentration of cerebral dopamine beta-hydroxylase in the hypothalamus and brain stem after experimental subarachnoid haemorrhage in rabbits. Clonidine dopamine beta-hydroxylase Oryctolagus cuniculus