Title : Tetraarsenic oxide, a novel orally administrable angiogenesis inhibitor.

Pub. Date : 2003 Jun

PMID : 12738993






2 Functional Relationships(s)
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1 In in vitro studies, tetraarsenic oxide inhibited the proliferation (IC50 = 99.7 nM), migration into the denuded area (IC50 = 27.4 nM), and invasion through a layer of Matrigel (IC50 = 73.5 nM) of basic fibroblast growth factor (bFGF)-stimulated bovine capillary endothelial (BCE) cells in a dose-dependent manner. Arsenic Trioxide fibroblast growth factor 2 Bos taurus
2 In in vitro studies, tetraarsenic oxide inhibited the proliferation (IC50 = 99.7 nM), migration into the denuded area (IC50 = 27.4 nM), and invasion through a layer of Matrigel (IC50 = 73.5 nM) of basic fibroblast growth factor (bFGF)-stimulated bovine capillary endothelial (BCE) cells in a dose-dependent manner. Arsenic Trioxide fibroblast growth factor 2 Bos taurus