Title : Effect of apoptogenic stimuli on colon carcinoma cell lines with a different c-myc expression level.

Pub. Date : 2003 Jun

PMID : 12736715






1 Functional Relationships(s)
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1 Our results indicate that cells with endogenous or transfected exogenous c-myc overexpression (SW613-12A1 and -2G1mycP2Tu1 cell lines, respectively), activate the apoptotic machinery in response to the treatment with etoposide, doxorubicin and vitamin D3, which induce apoptosis through the death receptor Fas. Cholecalciferol MYC proto-oncogene, bHLH transcription factor Homo sapiens