Title : Improved gelatinase a selectivity by novel zinc binding groups containing galardin derivatives.

Pub. Date : 2003 May 19

PMID : 12729664






2 Functional Relationships(s)
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1 The synthesis of several analogues of galardin, a MMP inhibitor, are presented with their in vitro inhibitory activity against MMP-1 and MMP-2. N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide matrix metallopeptidase 1 Homo sapiens
2 The synthesis of several analogues of galardin, a MMP inhibitor, are presented with their in vitro inhibitory activity against MMP-1 and MMP-2. N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide matrix metallopeptidase 1 Homo sapiens