Title : PTHrP [67-86] regulates the expression of stress proteins in breast cancer cells inducing modifications in urokinase-plasminogen activator and MMP-1 expression.

Pub. Date : 2003 Jun 15

PMID : 12724357






1 Functional Relationships(s)
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1 In fact, our data show that incubation of PTHrP [67-86]-amide-treated cells with either antisense hsbp1-oligonucleotide or geldanamycin, an hsp90-inactivating antibiotic, results in downregulation of uPa and upregulation of MMP-1, and in a prominent inhibition of cell invasion in matrigel-containing Transwell chambers. Oligonucleotides heat shock protein 90 alpha family class A member 1 Homo sapiens