Title : A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides.

Pub. Date : 2003 May

PMID : 12717453






2 Functional Relationships(s)
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1 Considering the enzymatic parameters of MTH1 and NUDT5 for oxidized guanine nucleotides, NUDT5 might have a much greater role than MTH1 in preventing the occurrence of mutations that are caused by the misincorporation of 8-oxoguanine in human cells. Guanine Nucleotides nudix hydrolase 1 Homo sapiens
2 Considering the enzymatic parameters of MTH1 and NUDT5 for oxidized guanine nucleotides, NUDT5 might have a much greater role than MTH1 in preventing the occurrence of mutations that are caused by the misincorporation of 8-oxoguanine in human cells. Guanine Nucleotides nudix hydrolase 1 Homo sapiens