Title : Human RPE-monocyte co-culture induces chemokine gene expression through activation of MAPK and NIK cascade.

Pub. Date : 2003 May

PMID : 12697421






2 Functional Relationships(s)
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1 In addition, anti-inflammatory drugs dexamethasone (DEX) and cyclosporin A (CSA) both blocked activation of JNKS/SAPK and the cell-cell contact induced production of hRPE IL-8 and MCP-1, while activation of p38 and ERK was only inhibited by DEX, but not by CSA. Dexamethasone C-C motif chemokine ligand 2 Homo sapiens
2 In addition, anti-inflammatory drugs dexamethasone (DEX) and cyclosporin A (CSA) both blocked activation of JNKS/SAPK and the cell-cell contact induced production of hRPE IL-8 and MCP-1, while activation of p38 and ERK was only inhibited by DEX, but not by CSA. Dexamethasone C-C motif chemokine ligand 2 Homo sapiens