Title : H-Ras modulates N-methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity.

Pub. Date : 2003 Jun 27

PMID : 12695509






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tyrosine phosphorylation of the NR2A and NR2B subunits of the N-methyl-d-aspartate (NMDA) receptor by Src protein-tyrosine kinases modulates receptor channel activity and is necessary for the induction of long term potentiation (LTP). Tyrosine SRC proto-oncogene, non-receptor tyrosine kinase Rattus norvegicus
2 Cotransfection of H-Ras and Src inhibited Src activity and decreased NR2A tyrosine phosphorylation. Tyrosine SRC proto-oncogene, non-receptor tyrosine kinase Rattus norvegicus