Pub. Date : 2003 Apr
PMID : 12691916
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: Experiments on human erythropoietin (EPO) demonstrated that there is a direct relationship between the sialic acid-containing carbohydrate content of EPO, its circulating half-life, and in vivo bioactivity. | Carbohydrates | erythropoietin | Homo sapiens |
| 2 | OBJECTIVE: Experiments on human erythropoietin (EPO) demonstrated that there is a direct relationship between the sialic acid-containing carbohydrate content of EPO, its circulating half-life, and in vivo bioactivity. | Carbohydrates | erythropoietin | Homo sapiens |
| 3 | OBJECTIVE: Experiments on human erythropoietin (EPO) demonstrated that there is a direct relationship between the sialic acid-containing carbohydrate content of EPO, its circulating half-life, and in vivo bioactivity. | Carbohydrates | erythropoietin | Homo sapiens |
| 4 | CONCLUSIONS: Increasing the sialic acid-containing carbohydrate content beyond the maximum found in EPO leads to a molecule with a longer circulating half-life and thereby an increased in vivo potency that can be administered less frequently. | Carbohydrates | erythropoietin | Homo sapiens |