Title : Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release.

Pub. Date : 2003 Apr 18

PMID : 12684045






2 Functional Relationships(s)
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1 Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release. Ruthenium Red cytochrome c, somatic Homo sapiens
2 Cotreatment with ruthenium red markedly prevented the activation of caspase 3, cytochrome c release, and cell death, suggesting a role for intracellular Ca(2+) in this process. Ruthenium Red cytochrome c, somatic Homo sapiens