Title : Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase.

Pub. Date : 2003 Aug

PMID : 12676772






2 Functional Relationships(s)
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1 These complexes likely function to stabilize sGC as well as to provide directed intracellular transfer of NO from NOS to sGC, thus preventing inactivation of NO by superoxide anion and formation of peroxynitrite, which is a toxic molecule that has been implicated in the pathology of several vascular diseases. Superoxides guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus
2 These complexes likely function to stabilize sGC as well as to provide directed intracellular transfer of NO from NOS to sGC, thus preventing inactivation of NO by superoxide anion and formation of peroxynitrite, which is a toxic molecule that has been implicated in the pathology of several vascular diseases. Superoxides guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus