Title : Do altering in ornithine decarboxylase activity and gene expression contribute to antiproliferative properties of COX inhibitors?

Pub. Date : 2003 Apr 7

PMID : 12671717






2 Functional Relationships(s)
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1 Treatment with celecoxib produced dose- and time-dependent decrease in ODC activity. Celecoxib ornithine decarboxylase 1 Rattus norvegicus
2 Our study revealed that celecoxib and aspirin share the ability to inhibit ODC activity and alter the pattern of immediate-early gene expression. Celecoxib ornithine decarboxylase 1 Rattus norvegicus