Title : Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes.

Pub. Date : 2003 Mar

PMID : 12663518






1 Functional Relationships(s)
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Protein Name
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1 IP6 strongly increased the expression of CDKIs (cyclin-dependent kinase inhibitors), Cip1/p21 and Kip1/p27, without any noticeable changes in G1 CDKs and cyclins, except a slight increase in cyclin D2. Phytic Acid cyclin dependent kinase inhibitor 1A Homo sapiens