Pub. Date : 2003 Mar
PMID : 12646997
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities. | icariin | phosphodiesterase 4A | Homo sapiens |
| 2 | The inhibitory effects of icariin on PDE5 and PDE4 activities were investigated by the two-step radioisotope procedure with [(3)H]-cGMP/[(3)H]-cAMP. | icariin | phosphodiesterase 4A | Homo sapiens |
| 3 | RESULTS: Icariin and papaverine showed dose-dependent inhibitory effects on PDE5 and PDE4 activities. | icariin | phosphodiesterase 4A | Homo sapiens |
| 4 | The potencies of selectivity of icariin and papaverine on PDE5 (PDE4/PDE5 of IC(50)) were 167.67 times and 4.54 times, respectively. | icariin | phosphodiesterase 4A | Homo sapiens |