Title : Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.

Pub. Date : 2003 Mar 1

PMID : 12615712






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In response to UV irradiation, p53R2 and hRRM2 dissociate from p53 and p53R2, and hRRM2 and hRRM1 transfer to the nucleus and form an active RR complex to provide dNDPs for DNA repair. dndps tumor protein p53 Homo sapiens