Title : Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast cancer cells.

Pub. Date : 2003 Feb

PMID : 12612058






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Remarkably, tamoxifen induces transcription factors and genes involved in promoting cell cycle progression including fos, myc, myb, cdc25a, cyclins E and A2, and stk15 with kinetics that paralleled that of cells cycling in response to estrogen, even though tamoxifen-treated cells are not transiting through the cell cycle. Tamoxifen MYC proto-oncogene, bHLH transcription factor Homo sapiens