Title : The cyclin-dependent kinase inhibitors p27Kip1 and p21Cip1 cooperate to restrict proliferative life span in differentiating ovarian cells.

Pub. Date : 2003 May 9

PMID : 12609976






1 Functional Relationships(s)
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1 Cultured p27(Kip1), p21(Cip1) double-null granulosa cells maintained expression of steroidogenic enzymes and gonadotropin receptors through 8-10 passages and could undergo further differentiation in responses to cAMP accumulation. Cyclic AMP cyclin-dependent kinase inhibitor 1A (P21) Mus musculus