Pub. Date : 2003 Mar 3
PMID : 12604592
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |
| 2 | Although the chromosome-associated enzyme RCC1 is responsible for RanGTP production, the mechanism of generating and maintaining the RanGTP gradient in vivo remains unknown. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |
| 3 | Our kinetic modeling suggests that RCC1 couples its catalytic activity to chromosome binding to generate a RanGTP gradient. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |
| 4 | Successful nucleotide exchange dissociates the binary complex, permitting the release of RCC1 and RanGTP from the chromatin and the production of RanGTP on the chromatin surface. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |