Title : Tyrosine phosphorylation of occludin attenuates its interactions with ZO-1, ZO-2, and ZO-3.

Pub. Date : 2003 Mar 7

PMID : 12604349






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tyrosine phosphorylation of occludin attenuates its interactions with ZO-1, ZO-2, and ZO-3. Tyrosine tight junction protein 1 Homo sapiens
2 Results show that the amounts of ZO-1, ZO-2, and ZO-3 bound to tyrosine phosphorylated C-occludin were several fold less than the amounts bound to non-phosphorylated C-occludin. Tyrosine tight junction protein 1 Homo sapiens
3 These results demonstrate that tyrosine phosphorylation of occludin reduces its ability to bind ZO-1, ZO-2, and ZO-3, but not F-actin. Tyrosine tight junction protein 1 Homo sapiens