Title : PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway.

Pub. Date : 2003 Mar

PMID : 12595494






2 Functional Relationships(s)
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1 A natural ligand of LXRalpha, 25-hydroxycholesterol (25-OHC), had similar effects; when used together with PPAR agonists, an additive effect was observed, indicating co-operation between PPAR and LXRalpha in regulating ABCA1 gene expression. 25-hydroxycholesterol nuclear receptor subfamily 1 group H member 3 Homo sapiens
2 A natural ligand of LXRalpha, 25-hydroxycholesterol (25-OHC), had similar effects; when used together with PPAR agonists, an additive effect was observed, indicating co-operation between PPAR and LXRalpha in regulating ABCA1 gene expression. 25-hydroxycholesterol nuclear receptor subfamily 1 group H member 3 Homo sapiens