Title : Variability of intestinal expression of P-glycoprotein in healthy volunteers as described by absorption of talinolol from four bioequivalent tablets.

Pub. Date : 2003 Mar

PMID : 12587122






1 Functional Relationships(s)
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1 The low intrasubject variability of the AUC(0-infinity) after weekly administration of the tablets refers to a small intrasubject variability of the "absorption window" and elimination of talinolol that most likely depends on the expression of P-gp in the small intestine. talinolol phosphoglycolate phosphatase Homo sapiens