Title : Antithrombin III phenylalanines 122 and 121 contribute to its high affinity for heparin and its conformational activation.

Pub. Date : 2003 May 2

PMID : 12556442






1 Functional Relationships(s)
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Protein Name
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1 Kinetic and structural considerations suggest that Phe-122 and Lys-114 act cooperatively through non-ionic interactions to promote P-helix formation and ATIII binding to the pentasaccharide. Lysine serpin family C member 1 Homo sapiens