Title : Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha.

Pub. Date : 2003 Mar

PMID : 12554795






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In rodent liver, transcription of the gene encoding cholesterol 7alpha-hydroxylase (CYP7A1), which catalyzes the rate-limiting step in the classic bile acid synthetic pathway, is stimulated by the liver X receptor alpha (LXRalpha), a nuclear receptor for oxysterol metabolites of cholesterol. Oxysterols nuclear receptor subfamily 1 group H member 3 Homo sapiens