Title : High glucose impairs superoxide production from isolated blood neutrophils.

Pub. Date : 2003 Apr

PMID : 12552364






2 Functional Relationships(s)
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1 This study measured the acute effects of high glucose or the G6PD inhibitor dehydroepiandrosterone (DHEA) on the production of O(2)(-) from isolated human neutrophils. Superoxides glucose-6-phosphate dehydrogenase Homo sapiens
2 CONCLUSIONS: High extracellular glucose concentrations acutely reduce O(2)(-) production from activated neutrophils possibly through inhibition of G6PD. Superoxides glucose-6-phosphate dehydrogenase Homo sapiens