Title : Differential effects of superoxide dismutase isoform expression on hydroperoxide-induced apoptosis in PC-12 cells.

Pub. Date : 2003 Apr 11

PMID : 12551919






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Accordingly, the stable overexpression of Mn-SOD attenuated TBH-induced mitochondrial ROS generation and cell apoptosis. tert-Butylhydroperoxide superoxide dismutase 2 Rattus norvegicus
2 Collectively, our results support a role for mitochondrial ROS in TBH-induced PC-12 apoptosis that is attenuated by Mn-SOD overexpression and is independent of cellular GSH levels per se. tert-Butylhydroperoxide superoxide dismutase 2 Rattus norvegicus