Pub. Date : 2000 Sep
PMID : 12545818
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The purpose of this study was to determine the effects of hCG on cellular cAMP levels in gastric adenocarcinoma cells(SGC-7901). | Cyclic AMP | hypertrichosis 2 (generalised, congenital) | Homo sapiens |
| 2 | The results showed that hCG obviously increased cAMP levels in SGC-7901 cells in a dose-dependent and time-dependent manner. | Cyclic AMP | hypertrichosis 2 (generalised, congenital) | Homo sapiens |
| 3 | When the concentration of hCG increased from 10(-11) mol/L to 10(-6) mol/L, the cellular cAMP levels increased from about 2.1 pmol/mg protein to about 10 pmol/mg protein and were significantly different from the control(P < 0.01). | Cyclic AMP | hypertrichosis 2 (generalised, congenital) | Homo sapiens |
| 4 | These results suggest that hCG possibly exerts its effects on gastric cancer cells by activating adenylyl cyclase/cAMP signal transduction pathway. | Cyclic AMP | hypertrichosis 2 (generalised, congenital) | Homo sapiens |