Title : Simulated sunlight and benzo[a]pyrene diol epoxide induced mutagenesis in the human p53 gene evaluated by the yeast functional assay: lack of correspondence to tumor mutation spectra.

Pub. Date : 2003 Jan

PMID : 12538356






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ultraviolet (UV) light from the sun and polycyclic aromatic hydrocarbons, such as benzo[a]pyrene, are strongly implicated in the spectrum of p53 mutations found in human non-melanoma skin cancers and smoking-associated lung cancers, respectively. Polycyclic Aromatic Hydrocarbons tumor protein p53 Homo sapiens