Title : Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression.

Pub. Date : 2003 Jan

PMID : 12507911






3 Functional Relationships(s)
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1 Cholesterol increments were associated with decreased SR-B1, increased ABCA1, and increased HMG CoA reductase (HMGCR) protein and its mRNA. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus
2 Tubule (HK-2) cell culture data indicated that SR-B1 and ABCA1 levels are responsive to cholesterol supply. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus
3 These changes are associated with adaptations in SR-B1 and ABCA1 expression, which are physiologically appropriate changes for a cholesterol overload state. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus