Pub. Date : 2003 Jan 31
PMID : 12505434
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our data show associations between non-workplace Cd exposure and changes in the abundance of hepatic and renal cortical CYP4A11. | Cadmium | cytochrome P450 family 4 subfamily A member 11 | Homo sapiens |
| 2 | In liver the levels of immunochemically detectable CYP4A11 were positively correlated with tissue Cd content while in contrast CYP4A11 abundance was inversely correlated with kidney Cd burden. | Cadmium | cytochrome P450 family 4 subfamily A member 11 | Homo sapiens |
| 3 | In liver the levels of immunochemically detectable CYP4A11 were positively correlated with tissue Cd content while in contrast CYP4A11 abundance was inversely correlated with kidney Cd burden. | Cadmium | cytochrome P450 family 4 subfamily A member 11 | Homo sapiens |
| 4 | These observations suggest the potential for involvement of Cd as a mediator of CYP4A11 expression in kidney cortex and indicate that elevations in kidney Cd content may be involved in hypertension via alteration of the expression of this particular isoform. | Cadmium | cytochrome P450 family 4 subfamily A member 11 | Homo sapiens |
| 5 | Potential mechanisms by which Cd may alter CYP4A11 expression are discussed briefly. | Cadmium | cytochrome P450 family 4 subfamily A member 11 | Homo sapiens |